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The sensitivity of GLP-1 analogues to temperature and light means that the manufacturing process must be rigorous

Diabetes Res Clin Pract 2007;77:1749

One animal was dead just before drug treatment at day 0 in tirzepatide treatment group

This approach ensures that the nanomaterial will be activated primarily in the vicinity of pathogenic bacteria, which thrive in such environments and will remain inactive in the more neutral pH of healthy tissues, pH-responsive NPs are commonly made using materials like chitosan, which undergoes protonation in acidic conditions, leading to a release of encapsulated drugs or antimicrobial agents at infection sites